Antivirus exclusions

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Drives

M: 
Mail data drive (Exchange Server)
Q: 
Quorum database drive (SQL Server cluster)

Folders

%systemroot%\Cluster 
Cluster Server data
%systemroot%\IIS Temporary Compressed Files 
HTTP compression temp directory
%systemroot%\ntds 
NT Directory Services (Active Directory private data)
%systemroot%\ntfrs 
NT File Replication Service
%windir%\SoftwareDistribution\Datastore 
Windows Update or Automatic Update database
%windir%\SoftwareDistribution\Datastore\Logs 
WU or AU logs
%systemroot%\system32\dhcp 
DHCP Server
%systemroot%\system32\dns 
DNS Server
%systemroot%\system32\inetsrv 
IIS applications
%systemroot%\SYSVOL 
System Volume (Active Directory public data)

Files

.bak 
Backup file
.bkp 
Backup file
.cac 
.chk 
Checkpoint file (Exchange)
.dat 
Data file
.dbs 
Database file (SQL)
.ddf 
Device Description Framework file
.dit 
Directory Information Tree file (Active Directory)
.edb 
Exchange Database file (Exchange)
.evt 
Event Log file
.jrs 
Journal Reserve file (Exchange)
.ldf 
Log Data File (Exchange)
.loc 
Lock file
.log 
Log file
.mdf 
Master Database File (SQL)
.ndf 
Next (secondary) Database File (SQL)
.ptl 
.ptr 
.stm 
Exchange Streaming Database file
.tmp 
Temporary file
.trn 

References

Microsoft

Symantec

Personal tools